Biotin
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Product Name:
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Vitamin H
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Synonyms:
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D-Biotin; Biotin; Vitamin B7; Hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanoic acid; Vitamin H (D-Biotin); D-Biotin pure; VH; 5-(2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoic acid; 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid; 5-[(3aR,4S,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoic acid; 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; 5-[(3aS,4S,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; 5-[(3aR,4S,6aS)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; 5-[(3aR,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate; VH; BIOS H; Biotin(D-); D-biotin(VH); D-Biotin(Vitamin H)
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CAS RN.:
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58-85-5;22879-79-4
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EINECS:
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200-399-3
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Molecular Weight:
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244.3032
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Molecular Formula:
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C10H16N2O3S
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Product Name: Vitamin H / D-Biotin
Specification: ≥98.0%
Appearance: White Powder
Molecular Formula: C10H16N2O3S
Molecular Weight:244.31
CAS Number: 58-85-5
Biotin, also known as vitamin H or coenzyme R, is a water-soluble B-vitamin (vitamin B7).
It is composed of a ureido (tetrahydroimidizalone) ring fused with a tetrahydrothiophene ring. A valeric acid substituent is attached to one of the carbon atoms of the tetrahydrothiophene ring. Biotin is a coenzyme for carboxylase enzymes, involved in the synthesis of fatty acids, isoleucine, and valine, and in gluconeogenesis.
Specification:
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Product Name:
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D-Biotin
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Grade:
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USP 40
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Cas No:
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58-85-5
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EINECS:
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200-399-3
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ITEM
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SPECFICATION
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METHOD
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Assay
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97.7%-100.5%
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USP
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Characters
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White crystalline powder
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Visual
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Identification
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IR
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Match with the reference IR spectrum
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UPS
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Specific optical rotation
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+89°-+93°
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USP
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Reaction time
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Be similar to the reference solution
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USP
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Loss on drying
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≤0.4%
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USP<731>
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Related substances
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Any impurity
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≤1.0%
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USP
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Total impurities
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≤2.0%
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USP
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Microbial Test
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Total Plate Count
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<1000cfu/g
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USP<61>
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Yeast & Mold
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<100cfu/g
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USP<61>
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Escherichia coli
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Negative/g
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USP<62>
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Staphylococcus aureus
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Negative/g
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USP<62>
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Pseudomonas aeruginosa
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Negative/g
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USP<62>
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Entericbacteria
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Negative/g
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USP<62>
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Salmonella
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Negative/10g
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USP<62>
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Function:
1.Biotin(Vitamin H ) is the essential Nutrients of the retina,the Biotin deficiency could cause the Dry eyes, keratization, inflammation, even blindness.
2.Biotin(Vitamin H) can improve the body's immune response and resistance.
3.Biotin(Vitamin H) can maintain normal growth and development.
4.Biotin(Vitamin H) deficiency will cause reproductive functions recession, bad bone growth and the obstruction of embryo and early childhood growth.
5.To help fat, glycogen and the synthesis and metabolism of amino acids in the human body is normal;
6.To promote sweat glands, nerve tissue, bone marrow, the male gonads, the skin and hair of normal operation and the growth, relieve eczema, dermatitis symptoms;
7.To prevent white hair and hair loss, help to cure baldness;
8.To ease muscle pain; 10Promote the synthesis of urea and excretion, purine synthesis and biosynthesis of oleic acid.
9.For the treatment of atherosclerosis, stroke, lipid metabolism disorders, high blood pressure, coronary heart disease and blood circulation disorder diseases.
Application:
1.Hair Problems:
Biotin supplements are often recommended as a natural product to counteract the problem of hair loss in both children and adults.
The signs and symptoms of biotin deficiency include hair loss which progresses in severity to include loss of eye lashes and eye brows in severely deficient subjects. Some shampoos are available that contain biotin, but it is doubtful whether they would have any useful effect, as biotin is not absorbed well through the skin.
2.Cradle Cap (Seborrheic Dermatitis)
Children with a rare inherited metabolic disorder called phenylketonuria (PKU; in which one is unable to break down the amino acid phenylalanine) often develop skin conditions such as eczema and seborrheic dermatitis in areas of the body other than the scalp.
The scaly skin changes that occur in people with PKU may be related to poor ability to use biotin. Increasing dietary biotin has been known to improve seborrheic dermatitis in these cases.
3.Diabetes
Diabetics may also benefit from biotin supplementation. In both insulin-dependent and non-insulin-dependent diabetes,supplementation with biotin can improve blood sugar control and help lower fastin
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